Unlock Youthful Skin at 50+ with iS Clinical: Ergothioneine & Soy Isoflavones.

As a 52-year-old woman who loves laughing (and the crow's feet that come with it!), I embrace aging gracefully. But let's be honest, menopause brings some unwelcome changes: new fine lines, a hint of sagging, drier skin, even thinning hair. 

Instead of defaulting to injectables (no judgment—I've had Botox maybe five times in my life), this time, I dove into science and discovered two powerhouse ingredients in one of my favorite brands, iS Clinical, that are perfect for postmenopausal skin: Ergothioneine and Soy Isoflavones. These proven actives feel like "estr" gen-energy" for skin, helping firm, hydrate, and renew where low hormones left off.

In the sections below, I'll explain why each one matters and how iSClinical's collection leverages them.

Ergothioneine: Nature's Antioxidant for Aging Skin

Ergothioneine is a natural amino acid antioxidant (rich in mushrooms) that our skin craves after menopause. It's easily transported into cells and accumulates in mitochondria, where it protects the cells and DNA.

In practical terms, Ergothioneine is a free-radical fighter, neutralizing oxidative stress caused by UV light and pollution. It even chelates metal ions to prevent them from causing skin damage. It's anti-inflammatory, calming redness by inhibiting cytokines. All of this means that Ergothioneine helps preserve the skin's collagen and elastin (key to firmness) and protects the outer barrier, so the skin stays plump and hydrated. Studies show that it can diminish UV photodamage and support natural repair, resulting in fewer wrinkles and a brighter, more resilient complexion.

Key benefits of Ergothioneine for mature skin include:

• Potent Antioxidant: Scavenges free radicals (UV, pollution) and shields skin cells from oxidative aging. Ergothioneine helps fight free radicals, which can minimize the appearance of wrinkles, fine lines, and age spots.
• Anti-Inflammatory: Calms irritation and puffiness by reducing inflammatory signals in the skin.
• Cellular Energy Booster: Concentrates in mitochondria to preserve skin-cell vitality and DNA integrity.
• UV Defense & Repair: Reduces UV-induced photodamage and supports the skin's processes, which are key as estrogen protection wanes.

iS Clinical puts Ergothioneine into its Youth line for maximum effect. Youth Serum (facial) and Youth Body Serum both deliver this ingredient alongside other actives.

Youth Serum is all about Tightening, Smoothing, and Restorative results. Its advanced formula instantly smooths fine lines and firms sagging skin, while longer-term peptides (like Copper Tripeptide-1) boost new collagen.

Youth Body Serum, a lightweight hydrating spray, infuses vitamin B5, hyaluronic acid, and Ergothioneine to hydrate, smooth, and soften skin all over. Think of it as giving your body skin a tall drink of moisture plus an antioxidant shield.

Soy Isoflavones: Plant "Estrogen" for "Mature Skin

Soy isoflavones (genistein, daidzein, etc.) are phytoestrogens – plant compounds that mimic some effects of estrogen in the body. After menopause, our skin craves the support of estrogen for structure and hydration. Soy isoflavones step in by binding estrogen receptors in skin cells, helping to stimulate collagen and elastin production. The result? Firmer, thicker skin. In fact, a clinical study in postmenopausal women showed that six months of soy isoflavone supplementation significantly increased epidermal thickness and boosted collagen and elastic fibers in most participants. Other trials report that soy antioxidants improve wrinkles, pigmentation, and skin moisture. A 6-month study found that women supplemented with soy had 5–7% less wrinkle severity and up to 68% greater facial hydration.

Key benefits of Soy Isoflavones for menopausal skin include:

• Estrogen-like Firming: Mimic estrogens to boost collagen and skin elasticity, slowing the age related volume loss.
• Restores Thickness: Regular use leads to a visibly thicker epidermis and increased dermal collagen and elastin (studies have shown significant gains in both).
• Reduces Wrinkles & Dark Spots: Improves skin texture and tone – research reports fewer wrinkles and diminished hyperpigmentation.
• Deep Hydration: Triggers higher levels of hyaluronic acid in the skin, helping it retain moisture for a plumper, smoother appearance.

iS Clinical harnesses soy isoflavones in its Youth Intensive Crème. Youth Intensive Crème is a rich recovery cream that infuses soy estrogens with vitamin C, superoxide dismutase, and deep hydrators. Together, these creams work overnight to rebuild the skin's foundation, so you wake up to softer, more resilient skin.

iS Clinical Youth Collection – Shop Now

For women over 50 looking to embrace joyful aging, I recommend trying these formulas. I'm loving them!

iS Clinical's line combines Ergothioneine and Soy Isoflavones in powerful ways. Here's a rundown of the key products:

• Youth Serum – Facial serum with Ergothioneine and copper peptides (30ml, ~$166). Think Tightening, Smoothing, Restorative benefits. It instantly blurs fine lines and firms the skin, while building collagen for a lasting lift.
• Youth Body Serum – Full-body antioxidant mist (200ml, ~$29). Hydrates and nourishes skin with hyaluronic acid, vitamins, and Ergothioneine. Clinically shown to hydrate, smooth, and soften skin on the body – like a daily spa treatment in a bottle.
• Youth Intensive Crème – Luxurious night cream (50ml, ~$166). Rich formula with Soy Isoflavones and antioxidants to rebuild and plump skin as you sleep. It replenishes moisture and supports cell renewal for a smoother complexion by morning.

Treat yourself – add them to your cart and see how science and a smile can transform your skin.

Remember friend, those laugh lines are badges of a life well-lived. With Ergothioneine and Soy Isoflavones on our side, we can maintain firm, hydrated, and glowing skin at every age. I've taken a before/after journey with these products, so stay tuned for my updates. In the meantime, shop the iS Clinical collection today and give your skin the care (and joy!).

With love;

Karina

Sources: Scientific studies and product data was used to highlight these benefits proton-health.com.comkoatji.compmc.ncbi.nlm.nih.govpmc.ncbi.nlm.nih.govpmc.ncbi.nlm.nih.govisclinical.comisclinical.comisclinical.comisclinical.com